RCT for Electroconvulsive Treatment Followed by Cognitive Control Training

Conditions: Depressive Episode, Electroconvulsive Therapy, Cognitive Remediation

Sex: All

Ages: 18 Years – 70 Years

Phase: NA

Enrollment: 88

Sponsor: University Hospital, Ghent

Summary

Major depressive disorder (MDD) is worldwide one of the most prevalent and disabling mental health conditions. Electroconvulsive therapy (ECT) is a safe and effective treatment even though 6-month relapse rates are high. Cognitive side effects of ECT, such as reduced cognitive control, might trigger mechanisms that increase relapse in patients. As such, cognitive control training (CCT) holds promise as a non-pharmacological strategy to improve long-term effects of ECT (i.e., increase remission, and reduce depression relapse).

Eligibility Criteria

Inclusion Criteria:aged between 18 and 70 years oldcurrent major depressive episode with treatment resistanceeligibility and consent for ECT treatmentability to provide consent to studyExclusion Criteria:neurodegenerative disorder or MOCA < 18catatoniaschizophreniaalcohol use disorder in previous yearprior ECT treatmentinsufficient computer knowledge or analphabetism

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05683028). StuddyBuddy aggregates publicly available trial information.