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Recruiting NCT05679856

Vocal Cord vs Whole Laryngeal Radiotherapy for T1aN0 Glottic Cancer

Conditions: Larynx Cancer Stage I, Glottic Carcinoma

Sex: All

Ages: 18 Years – N/A

Phase: NA

Enrollment: 50

Sponsor: National Cancer Institute, Egypt

Location: Egypt

Summary

The primary objective of this prospective randomized clinical trial is to assess non inferiority in terms of local control achieved with single vocal cord hypofractionated radiotherapy compared to standard of care whole laryngeal radiotherapy in patients with T1aN0 glottic cancer . Secondary objectives include overall survival rate and to compare the Voice Handicap Index score between the 2 arms as well as acute and late toxicities. Patients are randomized in 1:1 ratio.

Eligibility Criteria

Inclusion Criteria:T10N0 glottic squamous cell carcinomaAbility to provide written informed consentEastern Cooperative Oncology Group performance status 0-2Exclusion Criteria:Previous head and neck irradiation.WHO performance status above 2.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05679856). StuddyBuddy aggregates publicly available trial information.