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NCT05677607
Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease
Conditions: ICAS - Intracranial Atherosclerosis, Cerebral Small Vessel Diseases
Sex: All
Ages: 30 Years – N/A
Enrollment: 300
Sponsor: Chinese PLA General Hospital
Location: China
Summary
The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.
Eligibility Criteria
Inclusion Criteria:Age ≥ 18 yearsAt least one intracranial artery ≥ 50% atherosclerotic stenosisModified Rankin Scale < 2Mini-mental State Examination > 24Exclusion Criteria:Concurrent ipsilateral extracranial artery ≥ 50% stenosisPregnant womenContraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)
Source: ClinicalTrials.gov (NCT05677607). StuddyBuddy aggregates publicly available trial information.
