Feasibility Study: IGNITE-TX (Identifying Texans at Risk for Hereditary Cancer) Intervention

To learn if using IGNITE-TX or other intervention (such as educational materials) can help to increase the rates of genetic testing among the family members of people who have been diagnosed with a hereditary cancer syndrome

ProbandsInclusion Criteria:18 years of age or olderSpeaks and/or reads English or SpanishResides in the state of TexasHas known deleterious/pathogenic mutation or suspected deleterious/pathogenic variant in BRCA1 or BRCA2 (HBOC) or MLH1, MSH2, MSH6, PMS2, or EPCAM (LS)Has access to the internet or phone and can send and receive email and/or text messages at a US telephone numberHas at least one at-risk relative who meets inclusion criteria for first-degree relativeExclusion CriteriaHas no at-risk relatives meeting inclusion criteriaHas negative germline genetic testing or only variant of uncertain significanceUnwilling or unable to provide consentAt Risk Relative (ARR)Inclusion Criteria:18 years of age or olderSpeaks and reads English or SpanishResides in the United StatesCan provide proof of deleterious/suspected deleterious HBOC or LS variant present in a firstdegree relative (biological mother or father, biological child, or full sibling)Has access to internet or phone and can send and receive email and/or text messages at a US telephone numberExclusion Criteria:Unwilling or unable to provide consentReports no known HBOC or LS variant within the familyHas already been tested for the variant identified in the probandAlready listed as an ARR for another proband