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NCT05676229
Probiotic Blend in Reducing Anthropometric Measurements in Obese Adults
Conditions: Obesity, Obesity; Endocrine, Overweight and Obesity, Overweight, Obesity and Other Hyperalimentation
Sex: All
Ages: 18 Years – 65 Years
Phase: PHASE2
Enrollment: 108
Sponsor: Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Location: Brazil
Summary
It is already known that dysbiosis, that is, qualitative and quantitative changes in the composition of the intestinal microbiota, can be associated with the development of a series of intestinal and extra-intestinal disorders.
Dysbiosis is reported in irritable bowel syndrome, inflammatory bowel disease, colorectal cancer, allergic diseases, non-alcoholic steatohepatitis, arteriosclerotic diseases, neurological diseases and metabolic syndromes, mainly diabetes and obesity.
Among the many factors that play a key role in obesity, a number of studies show the intestinal microbiota as an important contributor.
Many studies carried out with probiotics have shown that their administration can be effective in the prevention and treatment of obesity.
Furthermore, it is found that benefits for body weight, abdominal adiposity, anthropometric measurements and body composition are often associated with favorable metabolic effects.
Eligibility Criteria
Inclusion Criteria:Provision of Free and Informed Consent in writing, signed and dated;Age according to the indicated population (18-65 years old)both genders;Body mass index (BMI) of 25 - 35 Kg/m2.Exclusion Criteria:Pregnant and lactating womenIndividuals with a history of daily consumption of probiotics, fermented milk and/or yogurt; subjects known to have demonstrated a prior reaction, including anaphylaxis, to any substance in the composition of the study product;Individuals with concomitant participation in another clinical trial;History of autoimmune, cardiovascular, thyroid, or chronic liver disease;Making use of medication capable of affecting weight change, antidiabetic medication, hypolipidemic agents;Individuals who have undergone weight loss surgery,Weight change greater than 5% in the last three months.
Source: ClinicalTrials.gov (NCT05676229). StuddyBuddy aggregates publicly available trial information.