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Completed
NCT05675254
The Prevalence and Risk Factors of Coagulopathy in Pediatric Epilepsy Surgery Patients
Conditions: Epilepsy in Children, Coagulation and Hemorrhagic Disorders, Epilepsy; Seizure, Antiepileptic Adverse Reaction
Sex: All
Ages: 1 Month – 18 Years
Enrollment: 494
Sponsor: Children's Hospital of Fudan University
Location: China
Summary
The hematologic consequences of novel Anti-seizure medications (ASMs) are rarely reported.Whether coagulation dysfunctions increase the risk of peri-operative bleeding remains controversial.The research is performed to investigated the incidence and risk factors of preoperative coagulation dysfunction in children undergoing surgery for epilepsy and their impact on surgery.
Eligibility Criteria
Inclusion Criteria:Age<18 yearsA discharge diagnosis of "epilepsy" according to the International Classification of Diseases (ICD-10)Received surgical treatment for epilepsy during the hospitalizationHospitalized between January 2015 and December 2021 at the Neurosurgery Department of Children's Hospital of Fudan UniversityNon-epileptic children who underwent non-epilepsy neurological surgery by the same surgeon and were admitted at the same period for controlExclusion Criteria:The clinical information or laboratory examinations were incompleteHad concomitant diseases affecting coagulation or liver functionPatients or parents refused to be enrolled
Source: ClinicalTrials.gov (NCT05675254). StuddyBuddy aggregates publicly available trial information.
