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Recruiting
NCT05674877
Opioid Sparing Anesthesia in Patients With Liver Cirrhosis Undergoing Liver Resection
Conditions: Liver Cirrhosis
Sex: All
Ages: 18 Years – 65 Years
Phase: PHASE3
Enrollment: 50
Sponsor: Cairo University
Location: Egypt
Summary
This randomized clinical trial will investigate the opioid sparing effect of dexmedetomidine and ketmine infusion in cirrhotic patients undergoing liver resection
Eligibility Criteria
Inclusion Criteria:Male and female patients with liver cirrhosis [Child A] aged 18 to 65 years undergoing liver resection.American Society of Anesthesiologists class II-III.Exclusion Criteria:Renal or cardiac dysfunctionHistory of chronic painAlcohol or drug abuseAnalgesic use in last 24 hours before surgeryMajor intraoperative hemodynamic instabilityThe need for postoperative ventilationPsychiatric disordersInability to comprehend pain assessmentAllergy or contraindication to any of the study medications.
Source: ClinicalTrials.gov (NCT05674877). StuddyBuddy aggregates publicly available trial information.