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NCT05674331
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
Conditions: Alveolar Bone Loss
Sex: All
Ages: 18 Years – 99 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 63
Sponsor: Semmelweis University
Location: Hungary
Summary
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced.
Several materials and techniques have been advocated for ARP.
The aim of our randomised clinical trial is to evaluate the efficacy of extraction side development technique (XSD) and autogenous tooth bone graft (ATB) for ARP.
Eligibility Criteria
Inclusion Criteria:Women and men Patients over 18 years Co-operative patients with good individual oral hygiene (FMBS: 25%>) Patients with periodontal disease in treatment or under treatment with minimal active inflammation (FMPS: 25%>)Local criteria:Teeth with a hopeless prognosis with advanced periodontal or endo-periodontal defects, which are restored with implant prosthesis EDS 3-4 extraction defects after tooth extractionExclusion Criteria:Infectious diseases (HBV, HCV, HIV, CoV-2019…) Current chemotherapy or radiotherapy Previous radiation therapy to the head and neck region (in the last 2 years) Untreated insulin dependent diabetes mellitus Clinically significant osteoporosis or other systemic disease affecting bone metabolism Clinically significant circulatory disorder e.g.: decompensated cardiac failure Haemodynamically significant valvular heart failure or myocardial infarction within the last 3 months Clinically significant coagulopathy Current or previous systemic corticosteroid therapy (in the last 2 months) Current or previous systemic bisphosphonate therapy (beyond 30 days) Pregnant or breastfeeding women Smoking (max 5 cigarettes per day) Drug addiction, alcoholism
Source: ClinicalTrials.gov (NCT05674331). StuddyBuddy aggregates publicly available trial information.