New Treatment Perspectives in Adolescents With Anorexia Nervosa: the Efficacy of Non-invasive Brain-directed Treatment

The present randomized, double blind, placebo-controlled trial aims at evaluating the efficacy of a tDCS treatment in improving the clinical outcome of adolescents with AN and investigate brain mechanisms acting in AN.

Inclusion Criteria:diagnosis of AN according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition - DSM-5 (American Psychiatric Association & American Psychiatric Association, 2013);condition of under-weight (BMI <18.5 kg/m2);intelligence quotient higher or equal to 85 (IQ ≥ 85);ability to give informed consent under parents' surveillance and guidanceExclusion Criteria:a personal history of neurological/medical/genetic diseases;a personal history of epilepsy;suicide risk;receiving CNS-active drug, other counseling or psychological therapies during the treatment.