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Completed NCT05672771

The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults

Conditions: Cognitive Aging

Sex: All
Ages: 60 Years – 90 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 80
Sponsor: University of Illinois at Urbana-Champaign

Location: United States

Summary

While an intellectually active and socially integrated lifestyle shows promise for promoting cognitive resilience, the mechanisms underlying any such effects are not well understood. The aim of the current project is test the implications of the "mutualism" hypothesis, which suggests that intellectual function emerges out of the reciprocal influence of growth in abilities as they are exercised in the ecology of everyday life. Such a view implies that improvement in one component will enhance the modifiability of a related component. An additional aim was to test the idea that mutualistic effects will be enhanced by more diverse training in related skills, such as interleaved training of multiple skills, relative to single-component training.A "successive-enrichment" paradigm was developed to test this with working memory (WM) as the target for training given its centrality in models of attention, intellectual function, and everyday capacities such as reasoning and language comprehension. All participants receive the same target training, but the nature of the training that precedes it is manipulated. Outcome measures include pre- to posttest gains in working memory and episodic memory, as well as the rate of gain in learning the target task. The principle of enhanced mutualism would predict that more diverse experiences related to the target skill will enhance efficiency in acquiring the target skill.

Eligibility Criteria

Inclusion Criteria:Native English speakers or acquisition of English before age 6 yrs oldSelf-report of hearing ability sufficient to engage with lab personnelNo stroke in the last 3 yearsNo current cancer treatment involving radiation or chemotherapy - No self-reported learning disabilityNo self-reported psychiatric disorderWillingness to be randomly assigned to training conditionsNo plans that would limit participation during the activity periodNo participation in a cognitive intervention program in the last yearNo additional Exclusion Criteria.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05672771). StuddyBuddy aggregates publicly available trial information.