Hemodynamic Testing Strategies to Assess Pulmonary Hypertension in Heart Failure

The goal of this observational study is to learn about heart function and high lung blood pressure in patients with heart failure. The main question[s] it aims to answer are whether we can improve the ability to predict patients who will have complications after they receive treatment including heart transplant and left ventricular assist devices.

Inclusion Criteria:Adults age 18 years or olderHeart failure with reduced ejection fraction (<40%)referred for RHC at our centre for evaluation of candidacy for advanced HF therapies.Exclusion Criteria:Severe valvular or complex congenital heart disease Short-term mechanical circulatory support for progressive cardiogenic shock (e.g. extracorporeal membrane oxygenation) Acute coronary syndrome or revascularization occurred within 7 days prior to the RHC.Pregnant or breast-feeding Known hypersensitivity to sodium nitroprusside Advanced liver dysfunction Reduced capacity or inability to provide informed consent