Effect of Adding Hyaluronidase to Bupivacaine in Transversus Abdominis Plane Block for Cesarean Section

Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block. However, there have not been adequate studies to establish the efficacy of adding hyaluronidase in lateral TAP after cesarean section. Hence, the present study was carried out to evaluate the efficacy of hyaluronidase in different concentrations added to bupivacaine in US-guided bilateral lateral TAP block.

Inclusion Criteria:parturients who aged between 18-40 years oldwith ASA physical status grade II andscheduled for elective CS under spinal anesthesiaExclusion Criteria:patients with ASA grade III or IV,refusal to participate,emergency CS or complicated pregnancy,those with bleeding disorders or on anticoagulants,those with severe respiratory and cardiovascular diseases,having any local infection at the injection site,history of allergy to one of the used drugs,obese patients (body mass index ≥ 30 kg/m2).