CogMS - A Real-world Study Into Cognitive Impairment in People With Multiple Sclerosis

The present study will investigate the correlation between objective and subjective cognition in multiple sclerosis. The study will also investigate the impact of covariates such as fatigue and depression, the relationship with the Expanded Disability Status Scale (EDSS) and brain volumetrics as measured on magnetic resonance imaging (MRI). Additionally, the study will provide insights into patients' experiences with cognition, and the usability of the used objective cognitive assessments.

Inclusion Criteria:Providing a signed informed consentAged between 18 and 65 years oldMS diagnosis (CIS, RRMS)Absence of hand function problems which limit the use of a device like a smartphoneNo history of relapse with onset 30 days prior to start of studyNo other major neurological or psychiatric disordersNo history of cognitive rehabilitation treatmentExclusion Criteria:Disease duration longer than 15 yearsPatients with established cognitive disorders other than MSDrug and/or alcohol abuse