Early Prediction of Postpartum Glucose Metabolism Abnormalities in Gestational Diabetes Mellitus

This project is expected to screen reliable serum markers in pregnant women with gestational diabetes mellitus (GDM) by using metabolic profiling and lipid profiling clinical high-throughput mass spectrometry technology. We intend to build an early pregnancy prediction model for postpartum glucose metabolism abnormalities of GDM. At the same time, this project plans to develop a predictive management system based on this model, so that it can be widely used in clinical detection process, realize the advance of the early warning window period of abnormal glucose metabolism, and provide theoretical guidance for the early postpartum blocking of GDM to the outcome of abnormal glucose metabolism.

Inclusion Criteria:Plan to have routine prenatal examinations and give birth in the research centerGDM was diagnosed at 24-28 gestational weeksSingleton pregnancyWithout other pregnancy complicationsWilling to cooperate with the hospital to follow upExclusion Criteria:Have diseases that affect metabolic function or even threaten the life of the mother and fetus before pregnancy, such as diabetes, heart disease, liver and kidney diseases, thyroid diseases with drug, autoimmune diseases, malignant tumors, AIDS, etc.Fetus has a known deformity or genetic defectsIncomplete clinical data