ANNE Vital Sign System Remote Sleep Assessment

Sleep apnea is characterized by temporary pauses or stops to participant's breathing. Currently, sleep apnea is diagnosed using an in-lab sleep study, which involves spending a night in a sleep laboratory hooked up to wires on the head, chest, and legs. However, this is not feasible for many older adults. To overcome this barrier, the investigators will utilize an investigational vital signs monitor - the Advanced NeoNatal Epidermal (ANNE) Vital Sign System (Sibel Health, Evanston, IL,USA).The primary objective of this study is to test the hypothesis that sleep apnea is associated with accelerated cognitive decline in older adults at risk for dementia. The investigators will measure sleep apnea at baseline and 12 months later and relate this to cognitive function at the same time points.Sex-stratification will be used in analyses as appropriate. Qualitative feedback forms will be used to collect information about participant ease of use and experience with the ANNE Vital Sign System.

Inclusion Criteria:The only inclusion criteria for this study is that participants must have consented and enrolled into a CTU affiliated study. There are no additional inclusion criteria. Individuals from CTU affiliated studies will be asked to confirm their enrollment in a CTU affiliated study as part of the informed consent process for this study.For reference, inclusion criteria of CTU affiliated studies from which we will recruit may include, but are not limited to, the following list:Ages 60-85Sufficient proficiency in English or FrenchTechnical ability to participate in remote assessmentsMeets criteria for No Dementia and one of the following (according to CCNA Criteria):Cognitively UnimpairedCognitively Unimpaired plus Subjective Cognitive ImpairmentMild Cognitive Impairment (MCI)AND Classified as being at increased risk of dementia based on at least one of the following: a. First-degree family history of dementia b. Self-Reported or documented current and/or history at midlife (45-60 years) of the following risk factors: i. Hypertension ii. Hypercholesterolemia iii. Body Mass Index > 30 kg/m2 iv. Physical Inactivity v. Insomnia vi. Vascular-metabolic riskExclusion Criteria:Known nickel allergyKnown cardiac implantable deviceKnown arrhythmiasOtherwise unable to use the sensors; for example, finger amputationsFor reference, exclusion criteria of CTU affiliated studies from which we will recruit may include, but are not limited to, the following list:Participants who, in the opinion of the investigator, are not able to complete trial procedures remotely or adhere to the schedule of study assessments.Individuals where English or French is not sufficiently proficient for remote clinical assessment.Individuals who do not have the technical ability. Technical ability is defined as having computer and internet access; ability to send and receive emails; ability to participate in remote assessments.Individuals who have a clinical diagnosis of DementiaClinical Dementia Rating (CDR; telephone/video-conference administration) Score of >1 or having a diagnosis of dementia based on DSM-IV criteriaTotal Score on the Montreal Cognitive Assessment (MoCA; video-conference administration) <13