Transcutaneous Tibial Nerve Stimulation in Antimuscarinic Naive and Refractory Women With Idiopathic Overactive Bladder

In this study is the first prospective trial that compares the efficacy of TTNS in antimuscarinic naive and refractory women with idiopathic OAB. In this study, it was aimed to compare the effectiveness of TTNS on quality of life (QoL) and clinical parameters related to OAB in antimuscarinic naive and refractory women. The results of this study would make it easier to understand the place of TTNS among the treatment options in women with idiopathic OAB.

Inclusion Criteria:Women 18 years and older with clinically idiopathic OABHaving the ability to give written informed consentAbility to understand proceduresExclusion Criteria:Presence of active vaginal or urinary tract infection or malignancyPregnancy or intention to become pregnant during the studyHistory of neurogenic bladder, peripheral or central neurological pathologyPresence of Grade 2 and higher pelvic organ prolapse (POP) according to the International Continence Society (ICS)Having undergone urogynecological surgery in the last 3 monthsWomen with stress urinary incontinenceHistory of PTNS and/or TTNS for OAB in the past 6 monthsPresence of a pacemaker or implanted defibrillatorPresence of anatomical or post-traumatic malformations / skin disorders of the tibial nerve region of the inner ankle that do not allow the application of electrodesPTK strength less than 3/5 (rated as modified Oxford scale, min: 0-max: 5)Ultrasonographic evidence of a postvoid residual urine volume greater than 100 ml