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Completed NCT05667051

Endocan Biomarker Level in Gingival Crevicular Fluid in Periodontitis Patients With Type 2 Diabetes Mellitus

Conditions: Periodontitis, Diabetes Mellitus

Sex: All

Ages: 40 Years – 65 Years

Enrollment: 42

Sponsor: Alexandria University

Location: Egypt

Summary

Aim of the current study was to evaluate Endocan biomarker level in gingival crevicular fluid of patients with stage 1 or 2 (mild to moderate) periodontitis with controlled type 2 diabetes mellitus (DM) and compare it to that in DM free periodontitis patients.

Eligibility Criteria

Inclusion Criteria:Probing pocket depths (PPD) ≤ 5 mm.Clinical attachment level (CAL) ≤ 4 mm.Type 2 DM, for at least the past 3 years.HbA1c ≤ 7%.Exclusion Criteria:Uncontrolled Diabetes Mellitus.Systemic antibiotic or anti-inflammatory medication use in the previous 2 months.Non-surgical periodontal therapy in the previous 6 months.Surgical periodontal therapy in the previous 12 months.Use of calcium channel blockers, phenytoin, or cyclosporine.Pregnancy.Smokers

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05667051). StuddyBuddy aggregates publicly available trial information.