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NCT05666765
Comparison Between Isotretinoin, Silymarin and Both in the Treatment of Acne Vulgaris
Conditions: Acne Vulgaris
Sex: All
Ages: 16 Years – N/A
Phase: PHASE4
Enrollment: 75
Sponsor: Tanta University
Location: Egypt
Summary
This study aims to compare the effects of isotretinoin and silymarin or both in treatment of acne and their effects on the level of IGF-1, SAA1 and malondialdehyde (MDA) in acne patients.
Eligibility Criteria
Inclusion Criteria:Age: 16 years or more.
Patient with moderate or severe acne.
Not receiving acne treatment in the last month.Exclusion Criteria:Pregnancy or lactation.
Patients with known hypersensitivity to isotretinoin or silymarin.
Patients with depression, liver diseases or high cholesterol.
Patients with acromegaly.
Patients with chronic inflammatory, infective or neoplastic disorders.
Source: ClinicalTrials.gov (NCT05666765). StuddyBuddy aggregates publicly available trial information.
