NIEHS Repository of Stored Biological Samples for Future Use

Background: Laboratory tests that use blood and urine can provide a great deal of information about human health and disease. To develop even better tests and to improve the ways samples are handled for testing researchers need to experiment with samples from healthy people. Objective: This natural history study will collect blood and urine from healthy people. The samples will build a repository that will be used for all kinds of research. Eligibility: Healthy people aged 18 years or older. Design: Participants will have 1 study visit. The visit will last up to 2 hours. Participants will be screened. They will answer questions about their health history. They will list any medications they take. They will consent to donate samples for research and future use: Blood: Up to 4.5 tablespoons of blood may be collected from a needle inserted into a vein. Urine: Participants will be given a sterile container to provide a sample. Some participants may be asked to provide other types of samples. Some participants may be asked to provide new samples if their first ones are depleted.

* INCLUSION CRITERIA: Inclusion Criteria for prospective biospecimen collection: To be eligible to participate in this study, an individual must meet all the following criteria: 1. Stated willingness to comply with all study procedures and availability for the duration of the study. 2. Ability to provide informed consent. 3. Male or female, aged \>=18 4. Able to travel to the NIEHS CRU for study visits EXCLUSION CRITERIA: Exclusion Criteria for prospective biospecimen collection: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Not willing to have samples stored for future use. 2. Any condition that, in the investigator s opinion, places the participant at undue risk for complications associated with required study procedures.