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NCT05666219
Reversal of Complete Heart Block With Aminophylline in Inferior Wall Myocardial Infarction Patients
Conditions: Complete Heart Block, Inferior Wall Myocardial Infarction
Sex: All
Ages: 18 Years – N/A
Phase: PHASE4
Enrollment: 73
Sponsor: National Institute of Cardiovascular Diseases, Karachi
Summary
In this study we will evaluate the rate of reversal of complete heart block with aminophylline in atropine resistant patients with inferior wall myocardial infarction (MI)
Eligibility Criteria
Inclusion Criteria:Adult patients admitted with recent acute inferior wall myocardial infarction (MI)Hemodynamically stable blood pressureComplete heart block with Narrow QRS < 120 ms and ventricular rate >40/min persisting for at least 6 hours resistant to atropineTemporary pacemaker (TPM) already placedPatient asymptomatic with mean arterial pressure of greater than 65 mmHg with TPM rate placed at 40/minExclusion Criteria:Patients with cardiogenic shockPatients with preexisting permanent pacemaker and Implantable Cardioverter Defibrillator (ICD).Patients with prior history of AV blockDrugs with dromo-tropic effects (beta blocker, calcium channel blocker, inotropes)Known liver disease (cirrhosis, hepatitis)HypothyroidismUnable to consent
Source: ClinicalTrials.gov (NCT05666219). StuddyBuddy aggregates publicly available trial information.
