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NCT05664412
Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome
Conditions: 22Q11 Deletion Syndrome, tACS
Sex: All
Ages: 14 Years – 25 Years
Phase: NA
Enrollment: 40
Sponsor: Stephan Eliez
Summary
The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2
microdeletion.
The main aim of the present research project is to investigate the effects of repeated, individually tuned high-density (HD) tACS on cognition (i.e., WM performance) and related neuroimaging markers in carriers of the 22q11DS.
As cognitive deficits, most notably WM impairment, are among the earliest signs of psychotic disorders, interventions during adolescence aimed at reducing cognitive decline in at-risk individuals may prove effective in delaying or even preventing the later emergence of psychotic symptoms.
Eligibility Criteria
Inclusion Criteria:Confirmed genetic diagnosis of 22q11DSAge between 14 and 25 years oldWillingness to participateInformed Consent signed by the subject and/or the caregiver(s)Exclusion Criteria:EpilepsyDeep brain stimulation electrodesTraumatic brain injuryFacial metal implants
Source: ClinicalTrials.gov (NCT05664412). StuddyBuddy aggregates publicly available trial information.
