Ruxolitinib as add-on Therapy in Steroid-refractory Graft-vs-host Disease
Conditions: Steroid Refractory GVHD
Sex: All
Ages: 3 Months – 30 Years
Phase: PHASE3
Enrollment: 6
Sponsor: Yi-Lun Wang
Location: Taiwan
Summary
Steroid-refractory graft-vs-host disease (SR-GVHD) is a major cause of mortality after allogeneic hematopoietic stem cell transplantation (HSCT).
We sought to evaluate the effect and safety of ruxolitinib (RUX) add-on in the treatment of patients with SR-GVHD.
Eligibility Criteria
Inclusion Criteria:Patients diagnosed with hematologic disorderExclusion Criteria:Those who are not applicable of receiving Ruxolitinib as immunodeficiency-modulation therapyThose who are actively encountering acute infectious illness
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