Effect of Thiamine on Serum Glucagon And Reactive Oxygen Spe... | Clinical Trial | StuddyBuddy@endsection Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS)
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Completed NCT05663164

Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS)

Conditions: Sepsis, Thiamine Deficiency

Sex: All
Ages: 18 Years – 65 Years
Phase: NA
Enrollment: 30
Sponsor: Universitas Sumatera Utara

Location: Indonesia

Summary

This research is a clinical trial with a Randomized Controlled Trial (RCT) design. The purpose is to identify the effect of intravenous thiamine administration compared to normal saline placebo on glucagon levels and ROS levels in patients undergoing general anesthesia surgery

Eligibility Criteria

Inclusion Criteria:Patients aged 18-65 years who undergo surgery under general anesthesiaASA physical statuses 1 and 2SepsisExclusion Criteria:Refuse to participateDiabetes mellitus, experience shock sepsis or lactic acidosisHave a history of hypersensitivity (allergy) to thiamineThiamine deficiencyTake immunomodulatory drugs, antiplatelet or anticoagulants surgery duration > 6 hours, and thiamin regularlyThey experience massive bleeding and receive blood transfusions preoperatively, intraoperatively, or postoperatively

Interested in this study? View the official listing for contact and enrollment details.

View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05663164). StuddyBuddy aggregates publicly available trial information.