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NCT05661487
Correlation MRI - Paraclinical Examination in Sudden Deafness Associated With Vertigo
Conditions: Vertigo Labyrinthine
Sex: All
Ages: 18 Years – N/A
Enrollment: 30
Sponsor: University Hospital, Strasbourg, France
Location: France
Summary
Acute cochleo-vestibular syndrome or labyrinthitis is characterized clinically by the sudden appearance of a great rotatory vertigo and a unilateral sensorineural hearing loss.
In this clinical context, MRI is the examination to eliminate differential diagnoses and to make a positive diagnosis of labyrinthitis (supposedly infectious, immunologic or ischemic).
The etiologies described are ischemic, infectious or autoimmune, so the risk factors are very variable (cardiovascular, autoimmune or infectious).Labyrinthitis has been little studied as a clinical entity in its own right.
Indeed, studies mainly focus on sudden deafness with subgroups of patients with vertigo.The incidence of sudden deafness is of the order of 5 to 20 per 100,000 people per year but is probably under-diagnosed.The individual and medico-economic consequences are similar to those of hearing loss, with an increased risk of dementia, depression, premature death and an increase in health care consumption.
Eligibility Criteria
Inclusion criteria:Patient of legal age (≥18 years)MRI diagnosis of labyrinthitis (presumed to be viral, immunologic, or ischemic in origin) at the University Hospitals (HUS) of Strasbourg between 01/01/2014 and 04/30/2021Patient with abrupt deafness (a 30 dB drop in hearing thresholds on at least 3 contiguous frequencies for at least 72 hours) associated with unilateral grand rotatory vertigo of abrupt onsetPatient with severe unilateral acute onset rotary vertigo with acute unilateral hypoacusis.Subject who did not express his opposition, after information, to the reuse of his data for the purpose of this research.Exclusion criteria:Subject who expressed opposition to participating in the study.History of chronic vertigo,Chronic dizziness,Presence of a differential diagnosis on MRI (intra-labyrinthine shwannoma, intra-labyrinthine hemorrhage or complicated cholestatoma)History of surgery on the inner or middle ear.
Source: ClinicalTrials.gov (NCT05661487). StuddyBuddy aggregates publicly available trial information.