Clinical Feasibility of the Myotrace Measurement

To evaluate the feasibility of the MYOTRACE NRD (Neural Respiratory Drive) index as an aid to assess the respiratory status of a patient (improving or stable versus deteriorating) as compared to a specialist in thoracic medicine's evaluation in a general care setting.

Inclusion Criteria:Age 18+, fluent knowledge of English or German.Group A: Obstructive ventilatory disorders (conditions resulting in an increased load on the respiratory muscle pump due to hyperinflation ± pronounced hypoxaemia)Acute exacerbation of COPD (pronounced hypoxia OR acute or acute on chronic hypercapnic respiratory failure)Exacerbation of asthma bronchialeExacerbation of non-CF-bronchiectasis (infectious)Infectious exacerbation of lung disease in cystic fibrosisGroup B: Conditions with an increase in NRD due to an impairment in gas exchange (particularly die to diffusion limitation and/or ventilation-perfusion-mismatchExacerbation of an interstitial lung disease (e.g. Idiopathic pulmonary fibrosis (IPF), Non Specific Interstitial Pneumonia (NSIP), Connective tissue disease- associated interstitial lung disease CTD-ILD)Worsening of pulmonary arterial hypertension World Health Organisation (WHO) group 1 (e.g. due decompensated heart failure)Acute pulmonary embolismPneumonia (resulting in hypoxaemia)Exclusion Criteria:Obesity hypoventilation syndrome (rationale: NRD decreased)Obesity WHO III with Body Mass Index (BMI) > 40 kg/m2 (rationale: surface EMG signal quality low)Hypercapnic respiratory failure due to hypoventilation of central origin, e.g. opiate-induced, Congenital central hypoventilation syndrome, post stroke (rationale: central respiratory control affected)Neuromuscular disease affecting respiratory muscles, e.g. motor neurone disease, muscular dystrophy type Duchenne etc. (rationale: EMG signal quality etc. different)Decompensated heart failure with atrial fibrillation (rationale: central breathing disturbance common)Patients on chronic opioid therapy (e.g. chronic pain, methadone etc.) (rationale: reduced NRD)Self reported pregnancy