CompARing Long terM Outcomes in Chronic Stroke Survivors Across Investigational Assessments Following a Prescribed Upper Extremity Exercise Program

The purpose of the study is to compare assessments of arm function following a standard exercise program in chronic stroke patients.

Inclusion Criteria:Single qualifying stroke event as confirmed by CT or MRIAt least 1 month post strokeScore of at least 2-/5 on Manual Muscle Test for wrist flexors or extensors, indicating adequate movement to complete robotic device useAble to follow written instructionsExclusion Criteria:Prior arm injury impacting available passive or active range of motion or significant arm pain with movementUnderlying brain pathologies such as metastatic or primary brain malignancies, comorbid multiple sclerosis, etc.Prior significant drug or alcohol abuseDiagnosed with dementiaPre-stroke baseline modified Rankin Scale (mRS) >3History of seizure/epilepsyHistory of clinically significant ischemic or hemorrhagic stroke prior to index stroke resulting in prior arm injury or weakness.PregnancyContraindication to MRI or Transcranial Magnetic Stimulation (TMS).Medical instability assessed by the treating stroke physician to participate to the study.