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NCT05659810
The Effect of Gabapentin on Spinal Anesthesia Duration
Conditions: Prolongation of Spinal Anesthesia
Sex: All
Ages: 20 Years – 60 Years
Phase: EARLY_PHASE1
Enrollment: 50
Sponsor: Ain Shams University
Location: Egypt
Summary
This prospective parallel group double blinded randomized study will be conducted over 50 adult participants between 20 and 60 years ASA (American Association of Anesthesiologists) I and II.
The participants will be randomly allocated in 2 groups.
Group A will receive 900 mg of gabapentin before surgery in 2 divided doses; 300 mg 10 hours prior to surgery and 600 mg 2 hours before surgery, while group B will receive 2 placebo tablets at the same time.
The participants will receive spinal anesthesia in the form of 3ml of hyperbaric bupivacaine 0.5%.
Hemodynamics will be recorded every 15 minutes till the end of surgery.
Sensory, and motor block progression, and regression will be recorded also.
Eligibility Criteria
Inclusion Criteria:American Society of Anesthesiologists class I, and IIAge 20 - 60 yearsWeight between 60 and 80 kilogramsHeight between 160 and 180 centimetresExclusion Criteria:Participants with contraindications to spinal anesthesia.Participant refusalExtreme short or tall staturesBody mass index above 40
Source: ClinicalTrials.gov (NCT05659810). StuddyBuddy aggregates publicly available trial information.