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NCT05658705
Preoperative Supine Time for Adrenal Venous Sampling
Conditions: Primary Aldosteronism
Sex: All
Ages: 18 Years – 80 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 120
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Location: China
Summary
This study aim to understand whether the length of preoperative supine time would affect the AVS outcome.
Eligibility Criteria
Inclusion Criteria:Patients are clinically diagnosed as primary aldosteronism with ARR≥37 (PAC showed as pg/ml, renin showed as μIU/mL) and passed through PA confirmatory tests (PAC-post CCT>110pg/ml, PAC-post SSIT >80pg/ml, or PAC-post FST>60pg/ml).
PAC: plasma aldosterone concentration;Patients with willing for AVS;Age 18 or above, male or female, with legal capacity.Exclusion Criteria:Patients with suspected adrenocortical carcinoma or pheochromocytoma;Patients with high risk of adrenal surgery;Patients have been subtyping to glucocorticoid-suppressible hyperaldosteronism or familial hyperaldosteronism type III;Patients were diagnosed as Cushing syndrome or subclinical Cushing syndrome;Patients were treated with glucocorticoids recently;Patients who refused to undergo unilateral adrenalectomy;Patients with whole body or venipuncture area infection;Patients with venous access thrombosis;Patients are allergic to iodine;Patients with X-ray contraindications;Patients with coagulation dysfunction;Patients are unable to cooperate and follow-up.
Source: ClinicalTrials.gov (NCT05658705). StuddyBuddy aggregates publicly available trial information.