Alternative Surveillance Program for Patients With High Risk Group of HCC

In a high-risk group, ultrasonography at 6-month intervals and short-protocol magnetic resonance imaging at 1-year intervals were performed. sensitivity, specificity, positive and negative predictive values for very early stage HCC are compared between conventional (biannual US) and alternative surveillance test are compared

Inclusion Criteria:chronic hepatitis B or CChild-Pugh classification AHCC risk score >= -2.04have not diagnosed with HCCon surveillance program using US and negative on previous US within 6-8 months of enrollmentsign informed consentExclusion Criteria:younger than 40 years or older than 70 years oldhistory of HCCsevere GFR or on HD/PD due to renal failurecontra-indication of MRIcongestive hepatopathyiron depositionpregnancy or nursing mothernon-viral hepatitis or liver cirrhosis