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NCT05657028
Dexmedetomidine Versus Lidocaine in Attenuating Airway Reflexes During Recovery of Thyroidectomy Patients
Conditions: Anesthesia, Airway Complication of Anesthesia
Sex: All
Ages: 18 Years – 65 Years
Healthy volunteers: 1
Phase: NA
Enrollment: 140
Sponsor: Ain Shams University
Location: Egypt
Summary
It is widely believed that most of the patients experience a cough upon emergence from general anesthesia, due to many causes including the presence of an endotracheal tube, uncleared secretions and anesthetic gas.
Cough during tracheal extubation may lead to several complications, such as hypertension, tachycardia and postoperative bleeding.In this study the investigators are going to compare the effectiveness of intravenous Dexmedetomidine and intravenous lidocaine in attenuating the air way reflexes and coughing during recovery of thyroidectomy patients.
Eligibility Criteria
Inclusion Criteria:Patients scheduled for elective thyroidectomy surgery.Age: patients between 18-and 65-years old from both sexes.Classified as either American Society of Anesthesiologists (ASA) class I or II.Exclusion Criteria:Refusal of procedure or participation in the study.Patients suffering from asthma, chronic cough, preoperative upper respiratory infection symptoms.Current smoker.Medication involving angiotensin-converting-enzyme inhibitors (ACE-I).Classified as either American Society of Anesthesiologists (ASA) class III or IV.Sinus Bradycardia (<60/min) or history of any type of heart block or Beta-Blockers medication.
Source: ClinicalTrials.gov (NCT05657028). StuddyBuddy aggregates publicly available trial information.