The Influencing Factors and Mechanism of High Incidence of Thrombotic Events in Patients With MN and DKD

Influence factors and preliminary mechanism of high incidence of thrombotic events in patients with idiopathic membranous nephropathy and diabetes kidney disease

Inclusion Criteria:Primary glomerular disease patients with renal biopsy results (without hormone or immunosuppressive therapy) and patients with clinical diagnosis of diabetes kidney disease;Age 18-70;The liver function is normal.Exclusion Criteria:Other secondary kidney diseases except diabetes; Acute renal injury; Chronic kidney disease stage 5;There are risk factors of hypercoagulability, such as acute infection, recent trauma, surgery or cancer, pregnancy;Anticoagulant and antiplatelet drugs were given within one week;Plasma infusion, plasma exchange or hemodialysis within one month;There is a history of thrombotic disease or hemorrhagic disease before renal puncture;Participated in other clinical studies within three months.