Ability of a Cat Food to Reduce Respiratory Symptoms in Cat Allergic Patients

Cat allergy is the most common animal allergy, affecting approximately 1 in 5 adults worldwide. The prevalence of allergy to furry animals is increasing, and cat allergy is a major risk factor for the development of asthma and rhinitis.Fel-d1 is the major feline allergen, to which 95% of cat allergic people react. All cats produce Fel-d1 regardless of breed, age, coat type, sex or weight. Fel-d1 is contained primarily in the saliva and sebum of cats.This allergy manifests itself as allergic rhinitis (AR) (sneezing, cold, coughing, conjunctivitis with watering and itching), severe asthma, and irritation and swelling of the skin when scratched.A new approach to managing cat allergies is to neutralize the allergens at the source by feeding domestic cats a diet containing anti-Fel-d1 IgY antibodies. The purpose of this pilot study is to determine whether feeding domestic cats a food containing an egg product with anti-Fel d1 IgY (PRO PLAN® LIVECLEAT®) induces a reduction of allergic symptoms in their owners.

Inclusion Criteria:Uncontrolled allergic rhinitis (with or without treatment)Persistent allergic rhinitis with worsening of symptoms upon exposure to catsPresence of one or two cats in the household, whose diet consists mainly of dry kibbleAgreement of the patient to change the food of the cat(s) and to feed it exclusively with the test kibbles during the study.Diagnosis of cat allergy defined by a positive prick test to standardized cat allergen or cat-specific IgE.Absence of allergy to pollens emitted in the region during the 4 months following the inclusion date, confirmed by a negative skin test.Person owning an android and/or IOS smartphone and having the possibility to connect to the internet (via phone subscription or WIFI connection),Person who agrees to install the MASK-air application (medical device) on his personal smartphone,Person having read and understood the information note and having signed their participation agreement before any specific procedure of the study.Exclusion Criteria:Person planning to be away from the cat(s) for more than one week/month in the 4 months following the inclusion visitPatient who has had a new cat in the home for less than one monthPatient in regular contact with other animals to which they are allergicPatient with uncontrolled asthmaPatient receiving immunotherapy for cat allergiesPatient participating or having participated in an allergic rhinitis study within the last 30 days or 5 half-lives of study medicationPerson who has difficulty understanding or reading the informationPerson declaring to be under guardianship, curatorship or safeguard of justice.