LA Improves the Prognosis of Patients With ICVD After Surgery

Ischemic cerebrovascular disease will cause serious harm to the life and safety of patients, and the treatment prognosis is poor. Numerous clinical trials have demonstrated that probiotics can improve cognitive function in people under multimodal. We have previously found that Lactobacillus acidophilus administration could improve cognitive impairment in MCAO and BCAS mice. Therefore, Based on the above research background and the basis of previous studies, we believe that the administration of Lactobacillus acidophilus solid drink (pure Lactobacillus acidophilus strain) can improve the cognitive function of patients with cerebral ischemia through the "brain-gut axis".

Inclusion Criteria:35-60 years old;Diagnosed as ischemic cerebrovascular disease, mild to moderate symptoms, can independently complete the neuropsychological test;No previous operation history;The modified Rankin scale score was 0 or 1;Carotid artery ischemic symptoms ≤3 months before treatment;Surgical treatment;Exclusion Criteria:Previous dementia;hearing or visual impairment;drugs that may or are known to affect cognitive abuse;alcohol addiction;Diagnosis of depression, schizophrenia and other mental diseases;MRI showed severe cerebral infarction;Patients with Lactobacillus acidophilus allergy.