Evaluation of the Use of the FUR to Quantify Tumor Glucose Consumption in Oncologic PET

The goal of this study is to evaluate the use of new method to quantify the amount of sugar a tumor consumes using PET/CT. The main questions it aims to answer are:Is the new quantification method superior with respect to the method currently used in the clinic?Does the new quantification method provide accurate assessment of the sugar consumption of tumours?Participants who will undergo a standard care FDG PET/CT scan will in additional receive a dynamic PET/CT scan prior to the standard care scan. In addition blood samples will be drawn at three time points during the examination.

Inclusion Criteria:Patients who receive an 18F FDG PET/CT scan as part of standard careBe competent and be 18 years of age or olderExclusion Criteria:Diabetes (fasted blood glucose > 7 mmol/L)Not fasted > 4 hoursPhysical exercise within 24 hoursEarlier treatment for carcinoma with radio/chemo-therapyActive inflammation (fever > 38 degrees, CRP > 5)Any condition or medical indication (such as claustrophobia) that indicates that the patient will not be able to lie still for the duration of the dynamic PET/CT examinationPregnant or breast feeding