Non-invasive Measurement of Arterial Stiffness

Reducing the risk of perioperative cardiovascular complications is a major issue for anesthesiology practice and research. Carotid-Femoral Pulse Wave Velocity (PWVcf)is a predictive, early and independent biomarker of cardiovascular events. Despite the unanimous support for PWVcf, it has not been widely used in routine clinical practice because of the complexity of the measurement method. Our team has developed a method to estimate PWVcf continuously in the operating room from the data obtained by the usual monitoring: an electrocardiogram (ECG), a digital photoplethysmography (PPG) and an oscillometric brachial sphygmomanometer for non-invasive blood pressure measurement (NIP). The objective of this study is to validate, during anesthesia, the method of estimation of PWV (obtained using the usual monitoring tools including the parameters derived from the SpO2 signal, NIBP and ECG) by comparing it to the reference method by measuring the carotid-femoral transit time obtained by Doppler effect. The measurement of the carotid-femoral transit time obtained by Doppler effect is totally non-invasive.

Inclusion Criteria:Patients of legal age ( 18 years)Eligible for a scheduled surgical procedure under general or locoregional anesthesia.Patients who have expressed no objection to participating in this researchExclusion Criteria:Patients under 18 years of age.Carotid or femoral space not availableAtrial fibrillation arrhythmia (AFA)Advanced obliterative arteriopathy of the lower limbs (grade III and IV - Leriche and Fontaine)Patient opposed to participation in the protocolPregnant womanPatient under judicial protectionPatient not affiliated to a social health system