MANTIS Endoscopic Clipping Study

This study is intended to document clinical effectiveness and safety pertaining to use of a new endoscopic clipping device MANTIS™ when used for hemostasis, closure, anchoring and marking.

Inclusion Criteria:Subject indicated for endoscopic clipping per local standard of practice.Willing and able to comply with the study procedures and provide written informed consent to participate in the study.Exclusion Criteria:Subjects who are currently enrolled in another investigational study that would directly interfere with the current study, without prior written approval from the sponsor.Subjects who the investigator deems at risk for study device or procedure related complications per the Instructions for Use (IFU). where commercially available or the Investigator Brochure (IB) for countries where the study device is not approved.