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Completed
NCT05651256
Efficacy of Botulinum Toxin in Temporomandibular Disorders
Conditions: Temporomandibular Joint Disorder Bilateral
Sex: All
Ages: 18 Years – 69 Years
Healthy volunteers: 1
Phase: PHASE2, PHASE3
Enrollment: 20
Sponsor: University of Salamanca
Location: Spain
Summary
Temporomandibular disorders (TMDs) represent a multifactorial pathological group that gives rise to a varied and complex symptomatology that includes decreased jaw movement, muscle and joint pain, joint crepitation and limitation or functional deviation of the jaw opening.All this is sometimes accompanied by headache and other painful symptoms in the neck musculature, incapacitating for many patients and at considerable public health expense.
Intramuscular and intra-articular injections of botulinum toxin are a simple treatment that has proven to be effective in the treatment of the painful symptoms of these disorders, being a therapeutic option in situations of failure of conventional treatments, without presenting adverse effects.Our study presents the preliminary results of twenty patients treated with this therapy
Eligibility Criteria
Inclusion Criteria:The study included patients diagnosed with TMDs, according to the established diagnostic criteria, aged between 18 and 69 years (both included) and with unilateral painful symptomatology of more than three months' duration.Exclusion Criteria:Patients previously treated with surgery/arthrocentesis of the TMJ; patients treated in the last six months with surgery in the cervicofacial region; patients who, at the time of inclusion in the study, were being treated in a "Pain Unit" and patients who had previously received treatment with BTX.
Source: ClinicalTrials.gov (NCT05651256). StuddyBuddy aggregates publicly available trial information.
