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NCT05650957
PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia
Conditions: Acute Respiratory Distress Syndrome, COVID-19, Pneumonia, Mechanical Ventilation Complication
Sex: All
Ages: 18 Years – N/A
Enrollment: 7145
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Location: Argentina
Summary
This study aims to compare epidemiology, management of invasive ventilation and outcomes in critically ill patients with COVID-19 ARDS and ARDS from another pulmonary infection.
The investigators will use individual patient data from four recently published large observational COVID-9 studies, including the 'Practice of VENTilation in COVID-19 patients' (PRoVENT-COVID) study, the 'Epidemiology of COVID-19 patients in the ICU' (EPICCoV) study, the 'SATI-COVID-19 - Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina: a Prospective, Multicenter Cohort Study' and the CIBERESUCICOVID - Personalized Risk and Prognosis Factors and Follow-up at One Year of the Patients Hospitalized in the Spanish Intensive Care Units Infected with COVID -19' study.
The investigators will use the individual patient data from ARDS patients with another pulmonary infection from the 'LUNG -SAFE - Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE' study and the 'ERICC - Epidemiology of Respiratory Insufficiency in Critical Care' study.
Eligibility Criteria
Inclusion Criteria:Cause for ARDS is COVID -19 (confirmed with polymerase chain reaction (PCR) and/or presence of typical abnormalities on chest computer tomography (CT) and/or X-ray) or a pulmonary infection from another origenMeeting a Berlin criteria for ARDSInvasive ventilationExclusion Criteria:Age < 18 yearsAny form of non-invasive ventilation
Source: ClinicalTrials.gov (NCT05650957). StuddyBuddy aggregates publicly available trial information.