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Not Yet Recruiting NCT05650437

Impact of Ultraviolet Radiation on Bone Density and Muscle Strength in Postmenopausal Women

Conditions: Postmenopausal Osteoporosis

Sex: Female
Ages: 50 Years – 65 Years
Phase: NA
Enrollment: 70
Sponsor: Cairo University

Location: Egypt

Summary

70 postmenopausal women, aged 50 to 60, who are vitamin D deficient and diagnosed with osteoporosis or osteopenia with T score of DEXA of lumbar spine (L1 to L4) was less than or equal -1 and their body mass index between 25 and 30 kg/m2. They will be divided into two groups by randomization. 35 postmenopausal women in Group (A) will undergo three weekly sessions of UV therapy in addition to routine aerobic activity and vitamin D supplements (800 IU) daily for three months. For three months, group (B), which consists of 35 postmenopausal women, will undergo daily aerobic exercise and vitamin D supplementation (800 IU) only.The amount of serum 25-hydroxyvitamin D was measured using ELISA kits, bone mineral density of lumber spine was measured by dual energy X-ray absorptiometry (DEXA), and the torque of knee flexors and extensors was evaluated using the Biodex System 3 isokinetic dynamometer,

Eligibility Criteria

Inclusion Criteria:Postmenopausal women who did not engage in any recreational physical activity in the previous three months Low bone mineral density (BMD) at their spine and/or femoral neck met the inclusion criteria.They are in good health. body mass index (BMI) ranged from 25 to 30 kg/m2, ages ranged from 50 to 60Exclusion Criteria:mental, neurological, Vestibular, cardiovascular, metabolic disease, musculoskeletal disorders with lower limb deformity, visual or hearing impairment undergone hormone replacement therapy. any medication that affected their balance or photosensitizing medications like aspirin, tetracycline, and Chlorothiazide

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Source: ClinicalTrials.gov (NCT05650437). StuddyBuddy aggregates publicly available trial information.