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Completed
NCT05649592
Imaging Characteristics of Chronic Lumbar Disc Herniation From the Perspective of Core Muscles and Subcutaneous Fat Tissue Thickness
Conditions: Lumbar Disc Herniation
Sex: All
Ages: 20 Years – 55 Years
Healthy volunteers: 1
Enrollment: 110
Sponsor: Zhan Yunfan
Location: China
Summary
Fat infiltration and atrophy of lumbar muscles are related to spinal degenerative conditions, which can be seen reliably on MRI scans of lumbar disc herniation (LDH) patients.
The aim of this study was to investigate the relationship between the degeneration of core muscles, obesity and chronic LDH.
Fifty-five healthy volunteers and fifty-five chronic LDH patients (the course of the disease is more than six months) were enrolled.
Core muscle percent fat and subcutaneous fat tissue thickness(SFTT) were used as the outcome measure, and logistic regression and independent samples t-test as the analytical methods to compare the relationship of the following five independent variables (erector spinae, rectus abdominis, [transversus abdominal, internal abdominal oblique, and external abdominal oblique muscle], lumbar multifidus, and psoas major muscles) and SFTT with LDH.
Eligibility Criteria
Inclusion Criteria:patients in good physical health; ②patients aged 20 to 55 years, including 20 and 55 years, male or female; ③patients who agree to participate in the study and sign the informed consent.Exclusion criteria:patients who performed lumbar and abdominal muscles exercises in the past; ②patients unable to tolerate magnetic resonance imaging or claustrophobia;patients who are deemed unsuitable for the clinical trial.Removing criteria:patients who decline participation of various reasons;patients unable to comprehend questions asked by the researchers; ③patients intolerant to necessary examinations.
Source: ClinicalTrials.gov (NCT05649592). StuddyBuddy aggregates publicly available trial information.
