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NCT05648565
Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis
Conditions: Chronic Rhinitis
Sex: All
Ages: 18 Years – 80 Years
Phase: NA
Enrollment: 36
Sponsor: The University of Texas Health Science Center, Houston
Location: United States
Summary
The purpose of this study is to assess the effectiveness of radiofrequency ablation (RFA) of the posterior nasal nerve (PNN) in chronic rhinitis (CR) patients by comparing patient reflective total nasal symptom score (rTNSS) and nasal obstruction symptom evaluation (NOSE) , peak nasal inspiratory flow (PNIF) , and levels of Type 2 cytokines pre- and post-procedure.
Eligibility Criteria
Inclusion Criteria:chronic rhinitis symptoms for at least 6 months (rhinorrhea, congestion, post-nasal drip)poor response to medical management that was attempted for at least 4 weeksa rTNSS score ≥6, as well as ≥2 for rhinorrhea, and ≥1 for congestion.Exclusion Criteria:active sinusitisrhinitis medicamentosarecurrent and ongoing epistaxisimmunodeficiency as defined by an illness or a history of sinus surgery.
Source: ClinicalTrials.gov (NCT05648565). StuddyBuddy aggregates publicly available trial information.