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Recruiting NCT05643157

Cellular Scale Measures of Short-Term Retinal Atrophy Progression

Conditions: Pentosan Polysulfate Sodium Maculopathy, Pigmentary Maculopathy, Toxic Maculopathy, Pigmentary Retinopathy, Interstitial Cystitis, Chronic

Sex: All
Ages: 18 Years – 70 Years
Enrollment: 10
Sponsor: Indiana University

Location: United States

Summary

Our goal is to determine the cellular scale changes that occur in subjects who have disease progression due to pentosan polysulfate sodium toxicity

Eligibility Criteria

Inclusion Criteria:A history of pentosan polysulfate sodium (Elmiron) usage for 5+ yearsDocumented retinal findings that are associated with pentosan polysulfate sodium toxicityExclusion Criteria:Presence of cataract or ocular media opacity that impedes retinal imagingIf standard pupil dilation imposes a risk to ocular healthDocumented severe dry eye on ocular examHigh refractive error (more than -/+ 6 Diopters)

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05643157). StuddyBuddy aggregates publicly available trial information.