← Back to all trials
Completed
NCT05642936
Stress Reduction and Atherosclerotic CVD in African Americans
Conditions: Atherosclerosis, Cerebral
Sex: All
Ages: 18 Years – N/A
Phase: NA
Enrollment: 197
Sponsor: Maharishi International University
Summary
This was a randomized, single blind, controlled, community-based trial comparing the clinical efficacy of the Transcendental Meditation program in reducing atherosclerotic CVD in 197 African American men and women with documented coronary artery disease (CAD) over a one-year treatment period.
After baseline testing, participants were randomly assigned to either a stress reduction program (Transcendental Meditation) or a standard health education program.
Eligibility Criteria
Inclusion Criteria:race/ethnicity: African American, self-identified, age: no upper limit, gender: male or female, minimum carotid artery intima medial thickness (IMT) of at least .72 mm for men and .65 mm for women ---- at baseline screening.
Other inclusion criteria in the absence of a minimum IMT score at baseline screening was diabetes, and/or myocardial infarction, coronary artery by-pass grafting (CABG) not within the last three months, and angiography indicating at least one vessel with 50% stenosis.Exclusion Criteria:myocardial infarction, unstable angina, CABG, percutaneous transluminal coronary angioplasty (PTCA), or stroke within the previous three months, carotid artery endarterectomy, arrhythmia - atrial fibrillation, second or third degree AV block, congestive heart failure - class III or IV or ejection fraction less than 30 %, clinically significant valvular heart disease, clinically significant hepatic or renal failure, major psychiatric disorders, current alcohol or other drug abuse dependency disorder, non-cardiac life threatening illness, and participating in a formal stress management program-
Source: ClinicalTrials.gov (NCT05642936). StuddyBuddy aggregates publicly available trial information.
