The PK/PD of Deoxycholic Acid Amphotericin B in Invasiv... | Clinical Trial | StuddyBuddy@endsection The PK/PD of Deoxycholic Acid Amphotericin B in Invasive Fungal Infection Patients With Sepsis/Septic Shock
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Completed NCT05642624

The PK/PD of Deoxycholic Acid Amphotericin B in Invasive Fungal Infection Patients With Sepsis/Septic Shock

Conditions: Fungal Infection

Sex: All
Ages: 18 Years – 80 Years
Enrollment: 20
Sponsor: Southeast University, China

Location: China

Summary

To explore the PK/PD of deoxycholic amphotericin B in invasive fungal infection patients with sepsis/septic shock;To compare the PK/PD of deoxycholic amphotericin B in invasive fungal infection patients with sepsis and septic shock.

Eligibility Criteria

Inclusion Criteria:Patients age more than 18 years old; Meet the criteria of Sepsis 3.0; Admitted to ICU; Patients were suspected or diagnosis of IFI,doctors determined the use of deoxycholic acid amphotericin B.Exclusion Criteria:Serum creatinine≥221umol/L; Deoxycholic acid amphotericin B or amphotericin B liposome were used for the past 7 days; Patients being treated with rifampicin; Unable to tolerate treatment of deoxycholic acid amphotericin B; BMI<18.5 or >30; Tumors; Pregnancy; Estimated time of survival<24h; Patients who participated in other studies within 30 days.

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05642624). StuddyBuddy aggregates publicly available trial information.