Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors

Conditions: Tumors of the Central Nervous System, Childhood Cancer Survivors

Sex: All

Ages: 16 Years – 40 Years

Healthy volunteers: 1

Enrollment: 60

Sponsor: I.M. Sechenov First Moscow State Medical University

Summary

The purpose of research is to study to adverse cardiovascular disorder and risks factors in childhood cranial and craniospinal tumors survivors. In this research the investigators investigate cardiological instrumental diagnostic, such as electrocardiography, echocardiography with the determination of global longitudinal strain, cardiopulmonary exercise test, and diagnostic of endothelial function by Angioscan for the prediction of cardiovascular complications after cranial and craniospinal radiotherapy and chemotherapy.

Eligibility Criteria

Inclusion Criteria:radiation and chemotherapy for cranial and craniospinal tumors in childhood or adolescencecompletion of the therapy at least one year before enrollmentsigned informed consentthere were three separate types of informed consent - for adults, for minors and for their parentsminors were signing informed consent in the presence of their parents.Exclusion Criteria:standard contraindications to exercise testinganemia, pregnancypsychiatric diseasealcohol or drug abuseactive malignancyacute infection

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View on ClinicalTrials.gov

Source: ClinicalTrials.gov (NCT05641636). StuddyBuddy aggregates publicly available trial information.