Radiosurgery Induced Ototoxicity in Patients Treated for a Vestibular Schwannoma

The investigators aim to study the impact of stereotactic radiosurgery, for the treatment of vestibular Schwannoma, on the cochlear, vestibular, gustatory, and facial nerve functions and compare it with a conservatively treated group. The predictive value of radiological tumor characteristics on hearing preservation and vestibular function will be also evaluated.Additionally, the investigators will invite patients with vestibular Schwannoma to fill out questionnaires to assess their quality of life.

Inclusion Criteria:Aged 18 years or abovePatients with unilateral VS treated either with SRS or MRI-based observation strategy, as proposed by the institution's skull base tumor board independently of the studyPatients willing to take part in the study and give their informed consentExclusion Criteria:Previous surgical or radiation therapy for VS (including SRS)Patients diagnosed with neurofibromatosis type IIPreexisting profound hearing loss, with a pure tone average (PTA) >90 and word recognition score (WRS) <10%, upon initial assessmentPrevious middle ear surgery of the affected earConcurrent treatment with other experimental drugs