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NCT05640518
External Validation of the VExUS Score for the Prediction of Acute Renal Failure in Cardiac Surgery
Conditions: Renal Failure, Acute Renal Failure, Renal Insufficiency, Acute Renal Insufficiency
Sex: All
Ages: 18 Years – N/A
Enrollment: 119
Sponsor: University Hospital, Grenoble
Location: France
Summary
Acute renal failure is a frequent complication associated with significant morbidity and mortality in postoperative cardiac surgery.The VExUS (Venous Excess UltraSound grading system) score was created to qualitatively assess this venous congestion, based on ultrasound data from patients obtained post operatively in cardiac surgery.
These data included: inferior vena cava diameter, Doppler flow of the suprahepatic veins, portal trunk and renal veins.This score is predictive of the onset of acute renal failure in the first 3 days after surgery.The VExUS score has not been validated in an external and prospective way in cardiac surgery.
Eligibility Criteria
Inclusion Criteria:Scheduled cardiac surgeryAffiliated to a social security systemExclusion Criteria:Emergency surgeryChronic renal failure defined by a glomerular filtration rate of less than 30ml/min or dialysis.renal transplant recipientsCirrhosis and portal hypertensionSetting up a left ventricular assist device implantationPatient under ECMO (ExtraCorporeal Membrane Oxygenation), intra-aortic balloon pump, or a mechanical circulatory support device such as IMPELLANo available operator to perform ultrasound scansPatients objecting to the use of their data in researchSubject under guardianship or subject deprived of freedomPregnant or breastfeeding womenResume surgery within 48 hours of scheduled surgeryLack of a trained operator to perform D+1 and D+2 ultrasound
Source: ClinicalTrials.gov (NCT05640518). StuddyBuddy aggregates publicly available trial information.