Effect of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction

This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + injectable platelet-rich fibrin (i-PRF). As primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.

Inclusion Criteria:unilateral or bilateral disc displacement without reductionlocalized pain on temporomandibular jointdecreased mouth opening, lateral and protrusive movementsExclusion Criteria:Malignant or inflammatory disordersprior surgical history of temporomandibular joint