Efficacy and Safety of New Mometasone Furoate Nasal Spray Formulation in Acute Rhinosinusitis Patients: A Randomized Clinical Trial

Seasonal and perennial allergic rhinitis, acute rhino sinusitis, and nasal polyposis are examples of common inflammatory disorders of the airway that significantly reduce patient health and quality of life. Intranasal corticosteroids are advised as part of treatment plans for each of these illnesses since they help to reduce inflammation and thus symptoms.Objective In order to assess the effectiveness and safety of a new nano formulation of Mometasone furoate nano-nasal spray (FM-NNS) for the treatment of allergic rhinitis. Mometasone Furoate Nano-nasal spray (FM-NNS) was compared with commercial available nasal spray named as MFNS.

Inclusion Criteria:Children and adults of age (10-50) who had a diagnosis of rhinitisAbility and willingness to understand and provide informed consent.Exclusion Criteria:Known current pregnancy.Current hospitalization.Unable to complete online questionnaires or adhere to study requirements.Kidney failure or dialysis; severe liver disease or cirrhosis.Any parathyroid conditions.Known current pregnancy.History of SARS-CoV-2 infection.