Time Restricted Eating and Innate Immunity

The goal of this cross over study is to investigate the effect of short term time restricted eating (TRE) on the innate immune system in patients with a history of myocardial infarction.

Inclusion Criteria:Adult (age >18 years)Diagnosed with a myocardial infarction (between 1 and 5 years ago)Body mass index between 20 and 35 kg/m2Able to understand, be motivated and follow the study related proceduresAble to understand and give written informed consentExclusion Criteria:Myocardial infarction (defined as an increase in cardiac enzymes in combination with symptoms of ischemia or newly developed ischemic ECG changes), coronary artery bypass graft surgery or other major (cardiovascular) surgery, stroke or transient ischemic attack (TIA) in the past 1 year prior to screening.Use of immunomodulatory drugsUse of drugs that need to be taken with food.Diabetes Mellitus type I and type IIMedical history of any disease associated with immune deficiency (either congenital or acquired, including chemotherapy, active malignancy, organ transplant) or auto immune diseaseClinically significant infections within 1 months prior to start of or during intervention period or control period (defined as fever >38.5).Vaccination <1 month before start of or during intervention or control period.Eating disorders